The current commercial alternative to Homesite seems to be TopStyle, also by Nick Bradbury (who has a talent for making good and uncluttered interfaces) – originally a CSS editor, but it evolved into a full-fledged web development editor. But Homesite got bought off and is now sold by Macromedia, and development has stagnated for quite a while.
The default commercial HTML+scripting editor for web developers used to be Nick Bradbury’s Homesite, and I used to have it around for years and even do the odd programming job with it (until I found Eclipse, which is much more suited for Java development). Also see my review at which also offers some reasons why all other editors I found suck )
Doesn’t have the ability to load multiple files in one window though. I believe it now also comes with sourcecode. Wonderfully clean standard Windows interface, no ugly buttons etc. offers two essential functions that are surprisingly rare with other editors: you can convert the character encoding and linebreaks of your files while editing them or when saving (which is essential for HTML and CGI script editing). Like Edo above I also used Notepad2, which doesn’t offer much automation or other advanced features but is still the best really light text editor I found, and it’s free.